As we enter the second year of the COVID-19 pandemic, vaccinations provide hope that the world will soon be back to normal. Vaccines that are based upon messenger RNA (mRNA) technology require two shots spaced several weeks apart for optimal efficacy. Therefore, the Seeker for this Challenge is interested in a new vaccine formulation that confers the same level of protection with a single injection.

Unlike traditional vector vaccines that are based upon modified forms of a live virus, mRNA vaccines contain instructions that allow the host cell to produce and display a harmless spike protein on its surface, thus triggering an antibody response. These vaccines often require extreme cold storage and multiple doses for full efficacy.

Do you have ideas to create one-dose mRNA vaccines that offer the same level of protection, helping to broaden vaccines programmes worldwide? Enter today!